After smoking weed from a Nuclear Power Plant, innocent Tromaville High School students mutate into sex-crazed psychos and the Honor Society’s turned into carnivorous, kinky cretins! Combining humor and horror in classic Troma fashion, CLASS OF NUKE ‘EM HIGH is crust punk exploitation at its finest.

In Stockholm 1982, two punk-loving 13-year-old girls decide to form a band to escape the horrors of middle school and irritate the teenage boy heavy metal group, Iron Fist. Lacking any musical talent, they recruit the help of a Christian girl they see playing guitar at the school talent show. Together, the three girls find friendship and resilience through the spirit of DIY punk rock.

Vince Lombardi High School keeps losing principals to nervous breakdowns because of the students' love of rock 'n' roll and their disregard of education. When new principal Togar comes along and tries to lay down the law, Ramones-adoring student Riff Randal is there to create as much chaos as possible, stopping at nothing to spread her love of rock music and fulfill her mission of meeting her idols to give them her songs.